The paper analyzes the current status and research on organization in largescale construction projects and their problems. To solve these problems, the paper, which makes use of systematology and metasynthesis methods, proposes the organizational basic principles chart in largescale construction project and makes the construction project organization’s 10 variables model and 10 dimensions metasynthesis theory in which these dimensions are analyzed and reduced. Then, the paper establishes organizational metasynthesis’ logical framework, structural framework, operational mechanisms and operational framework, as well as its human resources allocation plan in largescale construction project. Then the Yi Organization has been put forward. Finally, it was applied to the practice of construction projects, in which some good results were confirmed. The organizational metasynthetic mode in largescale construction projects is also suitable for huge projects organization and is valuable for organization theory.