初诊2型糖尿病患者服药依从性动态变化趋势及纵向预测因素

doi:10.16460/j.issn1008-9969.2020.19.058

摘要/Abstract

摘要： 目的分析初诊2型糖尿病患者服药依从性的动态变化趋势及其纵向的预测因素。方法以100例新确诊2型糖尿病患者为目标人群,利用糖尿病心理痛苦量表、用药信念量表、家庭关怀度指数问卷、Morisky药物依从性量表对患者进行资料收集;采用多元线性回归分析探讨确诊后第1天的糖尿病心理痛苦、用药信念、家庭关怀度对初诊2型糖尿病患者确诊后1、3及6个月的服药依从性影响。结果初诊2型糖尿病患者的服药依从性得分情况在确诊后1、3、6个月分别是（6.5±1.9）、（5.6±1.7）、（4.9±1.3）分;服药依从性呈动态下降趋势（P<0.05）。多元线性回归分析发现糖尿病心理痛苦程度对初诊2型糖尿病患者确诊1、3、6个月后服药依从性情况具有负向预测作用（P<0.05）;用药信念对初诊2型糖尿病患者确诊1、3、6个月后服药依从性情况具有正向预测作用（P<0.05）;家庭关怀度对初诊2型糖尿病患者确诊3、6个月后服药依从性情况具有正向预测作用（P<0.05）。结论 2型糖尿病患者在初诊半年内服药依从性情况总体呈现动态下降的趋势,糖尿病心理痛苦、用药信念和家庭功能均可在早期预测初诊2型糖尿病患者的服药依从性情况。

关键词: 2型糖尿病, 初诊, 服药依从性, 纵向研究, 影响因素

Abstract: Objective To analyze the dynamic change of medication compliance of newly-diagnosed patients with type 2 diabetes mellitus (T2DM) and its longitudinal predictors.Methods Totally 100 newly-diagnosed T2DM patients were surveyed by using Diabetes Distress Scale (DDS), the Beliefs About Medicine Questionnaire (BMQ), the Family APGAR (adaptation, partnership, growth, affection,resolve) index and Morisky Medication Adherence Scale(MMAS). Multiple linear regression was used to analyze the influence of diabetes distress, medication belief, and family care on medication compliance in the very day after the diagnosis, 1 month, 3 and 6 months after the diagnosis.Results The score of medication compliance 1 month, 3 and 6 months after the diagnosis was 6.5±1.9, 5.6±1.7 and 4.9±1.3 respectively, which was decreased dynamically (P<0.05). Multiple linear regression showed that diabetes distress was a negative predictor (P<0.05) but medication belief and family care were positive predictors (P<0.05) for medication compliance 1 month,3 and 6 months after the diagnosis.Conclusion Overall,T2DM patients demonstrate a dynamic decrease in terms of medication compliance in the first half year after the diagnosis and diabetes distress, medication belief, and family care are predictors for medication compliance in T2DM patients.

Key words: T2DM, newly diagnosed, medication compliance, longitudinal research, influence factor

中图分类号:

R473.5

罗欢, 邹树芳. 初诊2型糖尿病患者服药依从性动态变化趋势及纵向预测因素[J]. 护理学报, 2020, 27(19): 58-61.

参考文献

[1] Khan MAB, Hashim MJ, King JK, et al.Epidemiology of Type 2 Diabetes-global Burden of Disease and Forecasted Trends[J].J Epidemiol Glob Health, 2020, 10(1):107-111.DOI:10.2991/jegh.k.191028.001.
[2] Elgart JF, Silvestrini C, Prestes M, et al.Drug Treatment of Type 2 Diabetes: Its Cost Is Significantly Associated with Hba1c Levels[J].Int J Clin Pract, 2019,73(4):e13336.DOI:10.1111/ijcp.13336.
[3] Andanalusia M, Athiyah U.Medication Adherence in Diabetes Mellitus Patients at Tanjung Karang Primary Health Care Center, Mataram[J].Basic Clin Physiol Pharmacol, 2019,30(6).DOI:10.1515/jbcpp-2019-0287.
[4] AlQarni K, AlQarni EA, Naqvi AA, et al.Assessment of Medication Adherence in Saudi Patients with Type II Diabetes Mellitus in Khobar City, Saudi Arabia[J].Front Pharmacol, 2019(10):1306.DOI:10.3389/fphar.2019.01306.
[5] 郦杭婷,周娜,楼数慧.糖尿病患者服药依从性评估方法的研究进展[J].护理与康复,2019,18(9):29-34.DOI:10.3969/j.issn.1671-9875.2019.09.006.
[6] 杨青,刘雪琴.中文版糖尿病痛苦量表信效度评价[J].护理学报,2010,17(17):8-10.DOI:10.16460/j.issn1008-9969.2010.17.023.
[7] 唐娇,高玲玲,胡细玲,等.中文版特异性用药信念量表应用于2型糖尿病患者的信效度检验[J].护理学杂志,2019,34(21):25-28.DOI:10.3870/j.issn.1001-4152.2019.21.025.
[8] Smilkstein G.The Family APGAR: A Proposal for a Family Function Test and Its Use by Physicians[J].J Fam Pract,1978,6(6):1231-1239.
[9] 王洁,莫永珍,卞茸文.中文版8条目Morisky用药依从性问卷在2型糖尿病患者中应用的信效度评价[J].中国糖尿病杂志,2013,21(12):1101-1104.DOI:10.3969/j.issn.1006-6187.2013.12.013.
[10] 张艳,高珊,惠蓉,等.个案管理对门诊初发2型糖尿病患者代谢指标及自我管理能力的影响[J].护理学报, 2019, 26(6):55-59.DOI:10.16460/j.issn1008-9969.2019.06.055.
[11] Kretchy IA, Koduah A, Ohene-Agyei T, et al.The Association between Diabetes-related Distress and Medication Adherence in Adult Patients with Type 2 Diabetes Mellitus: A Cross-sectional Study[J].J Diabetes Res, 2020,2020:4760624.DOI:10.1155/2020/4760624.
[12] Liu SY, Huang J, Dong QL, et al.Diabetes Distress, Happiness, and Its Associated Factors among Type 2 Diabetes Mellitus Patients with Different Therapies[J].Medicine, 2020,99(11):e18831.DOI:10.1097/MD.0000000000018831.
[13] Hashimoto K, Urata K, Yoshida A, et al.The Relationship Between Patients’ Perception of Type 2 Diabetes and Medication Adherence: A Cross-Sectional Study in Japan[J].J Pharm Health Care Sci,2019(5):2.DOI:10.1186/s40780-019-0132-8.
[14] Shiyanbola OO, Unni E, Huang YM.The Association of Health Literacy with Illness Perceptions, Medication Beliefs, And Medication Adherence among Individuals With Type 2 Diabetes[J].Res Social Adm Pharm, 2018,14(9):824-830.DOI:10.1016/j.sapharm.2017.12.005.
[15] Gu L, Wu S, Zhao S, et al.Association of Social Support and Medication Adherence in Chinese Patients with Type 2 Diabetes Mellitus[J].Int J Environ Res Public Health, 2017,14(12):1522.DOI:10.3390/ijerph14121522.
[16] 蒋燕,刘安诺,章秋,等.家属参与式教育对2型糖尿病患者代谢指标影响的Meta分析[J].中国现代医学杂志,2019,29(13):56-63.DOI:10.3969/j.issn.1005-8982.2019.13.011.

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