老年肺癌患者衰弱现状及影响因素分析

doi:10.16460/j.issn1008-9969.2020.15.007

摘要/Abstract

摘要： 目的调查老年肺癌住院患者衰弱的发生现状并分析其影响因素。方法采用方便抽样法,选取广西某三级甲等肿瘤医院胸瘤外科146例60岁及以上的肺癌患者,应用一般资料调查表、中文版格列宁根衰弱指标量表、中文版Barthel指数进行问卷调查,采用多元线性回归分析老年肺癌患者衰弱的影响因素。结果在老年肺癌住院患者中,衰弱患者占36.3%,衰弱总分为（3.01±1.58）分,其中躯体衰弱（1.27±0.90）分,认知衰弱（0.58±0.49）分,社交衰弱（0.52±0.50）分,心理衰弱（0.65±0.49）分。多元线性回归分析结果显示：年龄、肺癌分期、疾病病程、合并多病、日常生活能力对老年肺癌患者衰弱得分影响有统计学意义（P<0.001）,5个因素共解释总变异的50.4%。结论老年肺癌患者在躯体、认知、社交、心理方面存在不同程度的衰弱状态,多种因素可影响其衰弱的发生,肿瘤专科医护人员应重视对该人群衰弱情况的评估,及时采取有效可行的干预措施,改善其生活质量,减轻医疗负担。

关键词: 老年人, 肺癌, 衰弱, 影响因素

Abstract: Objective To investigate the current status of frailty in elderly patients with lung cancer and analyze the influencing factors. Methods A total of 146 cases of lung cancer patients aged 60 and above in the department of thoracic oncology, a tertiary grade-A cancer hospital in Guangxi were selected by convenient sampling and were surveyed by using general information questionnaire, Chinese version of Groningen Frailty Index and Barthel index scale. The influencing factors were analyzed by multiple linear regression. Results The total score of frailty was 3.01±1.58, including physical frailty 1.27±0.90, cognitive frailty 0.58±0.49, social frailty 0.52±0.50, and mental frailty 0.65±0.49. Multiple linear regression showed that age, stage of lung cancer, course of disease, multiple diseases, and activities of daily living had statistically significant effects on frailty score of elderly lung cancer patients, which explained 50.4% of the total variance (P<0.001). Conclusion Elderly patients with lung cancer have different degrees of frailty in physical, cognitive, social and psychological aspects, and multiple factors can affect the occurrence of frailty. Tumor specialists should attach importance to the assessment of frailty in this population, and timely take effective and feasible intervention measures to improve their quality of life and reduce medical burden.

Key words: elderly, lung cancer, frailty, influencing factor

中图分类号:

R473.73

陈菲菲, 庞永慧, 茅乃权, 罗洁宁, 蔡道玲. 老年肺癌患者衰弱现状及影响因素分析[J]. 护理学报, 2020, 27(15): 7-11.

CHEN Fei-fei, PANG Yong-hui, MAO Nai-quan, LUO Jie-ning, CAI Dao-ling. Frailty of Elderly Patients with Lung Cancer and Its influence Factors[J]. Journal of Nursing, 2020, 27(15): 7-11.

参考文献

[1] Ethun CG, Bilen MA, Jani AB, et al.Frailty and Cancer: Implications for Oncology Surgery Medical Oncology, and Radiation Oncology[J]. CA Cancer J Clin,2017, 67(5):362-377. DOI:10.3322/caac.21406.
[2] Handforth C, Clegg A, Young C, et al.The Prevalence and Outcomes of Frailty in Older Cancer Patients: A Systematic Review[J]. Ann Oncol.2015,26(6):1091-1101. DOI:10.1093/annonc/mdu540.
[3] Driessen EJM, Van Loon JGM, Maas HA, et al.Geriatric Assessment for Older Patients with Non-small Cell Lung Cancer: Daily Practice of Centers Participating in the NVALT25-ELDAPT Trial[J].25-ELDAPT Trial[J]. Lung,2018,196(4):463-468. DOI:10.1007/s00408-018-0116-8.
[4] 中华人民共和国国家卫生健康委员会.原发性肺癌诊疗规范(2018年版)[J].肿瘤综合治疗电子杂志,2019,5(3):100-120. DOI:10.12151/JMCM.2019.03-16.
[5] 李峥,刘宇.护理学研究方法[M].北京:人民卫生出版社,2018.
[6] Peters LL, Boter H, Buskens E, et al.Measurement Properties of the Groningen Frailty Indicator in Home-dwelling and Institutionalized Elderly People[J]. J Am Med Dir Assoc, 2012,13(6):546-551. DOI:10.1016/j.jamda.2012.04.007.
[7] Baitar A, Van Fraeyenhove F, Vandebroek A, et al.Evaluation of the Groningen Frailty Indicator and the G8 Questionnaire as Screening Tools for Frailty in Older Patients with Cancer[J]. J Geriatr Oncol, 2013, 4(1):32-38.DOI:10.1016/j. jgo.2012.08.001.
[8] Xiang W, Cheng Y, Li Z, et al.Cross-cultural Adaptation and Validation of the Groningen Frailty Indicator in Chinese Nursing Home Residents[J]. Aging Clin Exp Res, 2020,32(6):1035-1042. DOI:10.1007/s40520-019-01178-7.
[9] 相玮. 格列宁根衰弱指标量表的信效度分析及应用[D].吉林:吉林大学,2019.
[10] 蔡业峰,贾真,李伟峰,等.中文版Barthel指数对多中心测评缺血性卒中患者预后的研究[J]. 中国脑血管病杂志,2007,4(11):486-490.
[11] Wang Y, Zhang R, Shen Y, et al.Prediction of Chemotherapy Adverse Reactions and Mortality in Older Patients with Primary Lung Cancer Through Frailty Index Based on Routine Laboratory Data[J]. Clin Interv Aging, 2019, 14(5):1187-1197. DOI:10.2147/CIA.S201873.
[12] Lu J, Cao LL, Zheng CH, et al.The Preoperative Frailty Versus Inflammation-based Prognostic Score:Which is Better as an Objective Predictor for Gastric Cancer Patients 80 Years and Older?[J]. Ann Surg Oncol, 2017, 24(3):754-762. DOI:10.1245/s10434-016-5656-7.
[13] 张艳,梁亚萍,孙铭薇,等.老年人衰弱的影响因素分析[J].中华疾病控制杂志,2019,23(2):140-145. DOI:10.16462/j.cnki.zhjbkz.2019.02.004.
[14] 曾朝霞,梁杰.老年冠心病患者合并衰弱综合征的影响因素研究[J].中国全科医学,2017,20(19):2347-2352. DOI:10. 3969/j.issn.1007-9572. 2017. 19. 011.
[15] Gill TM, Gahbauer EA, Han L, et al.The Relationship between Intervening Hospitalizations and Transitions between Frailty States[J]. J Gerontol A Biol Sci Med Sci, 2011,66(11):1238-1243. DOI:10.1093/gerona/glr142.
[16] 杨继平,石泽亚,周毅峰,等.老年衰弱患者术前评估管理证据汇总[J].护理学报,2019,26(7):34-39. DOI:10.16460/j. issn1008-9969.2019.07.034.
[17] 张国龙,李映红,翁慧雯.老年肺癌化疗患者衰弱情况及影响因素分析[J].现代医院,2018,18(12):1773-1775. DOI: 10.3969/j.issn.1671-332X.2018.12.017.
[18] 施亮,王增,俞婷婷,等.慢性病及其治疗药物可能会影响肺癌患者术后5年生存率(英文)[J].中国药学杂志,2017,26(2):147-155.DOI:10.5246/jcps.2017.02.014.
[19] Woo J, Zheng Z, Leung J, et al.Prevalence of Frailty and Contributory Factors in three Chinese Populations with Different Socioeconomic and Healthcare Characteristics[J]. BMC Geriatr, 2015, 15(1):163.DOI:10.1186/s12877-015-0160-7.
[20] Fried LP, Tan Gen CM, Walston J, et al.Frailty in Older Adults: Evidence for a Phenotype[J]. J A Biol Sci Med Sci, 2001,56(3):M146-M156. DOI:10. 1093/Gerona
[21] 靳瑜,窦丽亚,马慧珍.抗阻力运动对老年2型糖尿病伴衰弱患者的应用效果[J].护理学报,2019,26(3):51-55. DOI: 10.16460/j.issn.1008-9969.2019.03.051.

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