护理学报 ›› 2023, Vol. 30 ›› Issue (24): 38-42.doi: 10.16460/j.issn1008-9969.2023.24.038
妊娠期生活方式干预对妊娠期高血压疾病进展及母婴结局影响的Meta分析
黄丽华1, 翟巾帼2, 田金徽3, 孔淦霞1, 王雪岩2, 陈莉瑾2, 袁心愿2, 耿薪茜2, 陈昭桐2
- 1.东莞市妇幼保健院,广东 东莞 523057;
2.南方医科大学 护理学院 护理与助产循证中心,广东 广州 510515;
3.兰州大学 循证医学中心,兰州 甘肃 730099
摘要： 目的 探讨妊娠期生活方式干预对妊娠期高血压疾病的预防效果。方法 计算机检索Cochrane Library、PubMed、Web of Science、Embase、CINAHL、中国生物医学文献数据库、中国知网、万方及维普数据库,搜集妊娠期生活方式干预对妊娠期高血压疾病及相关母婴结局的随机对照试验,检索时限均从建库至2023年6月31日。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后,采用RevMan 5.4软件进行分析。结果 共纳入31个随机对照试验,包括12 737名研究对象。Meta分析结果显示：与对照组相比,妊娠期生活方式干预可有效预防妊娠期高血压疾病[RR=0.69,95%CI（0.57,0.85）,P=0.0004]、妊娠期高血压[RR=0.63,95%CI（0.45,0.88）,P=0.007]、子痫前期[RR=0.81,95%CI（0.66,0.99）,P=0.04]的发生。生活方式干预组的妊娠期糖尿病、剖宫产发生率,妊娠期总增重、巨大儿发生率、新生儿体质量均低于对照组;但2组分娩孕周、早产儿发生率差异无统计学意义（P>0.05）。结论 妊娠期生活方式干预可有效预防妊娠期高血压疾病、妊娠期糖尿病的发生,降低剖宫产和巨大儿的发生率,控制新生儿体质量和妊娠期总增重;但2组分娩孕周、早产儿发生率无统计学差异,仍需更多高质量的研究进一步验证结论。
中图分类号:
- R473.71
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