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护理学报 ›› 2021, Vol. 28 ›› Issue (14): 1-7.doi: 10.16460/j.issn1008-9969.2021.14.001

• 研究生园地 •    下一篇

乳腺癌患者癌症复发恐惧影响因素的Meta分析

刘瑾1, 路娜2, 张凤娃3, 牛晓丹1, 袁蓉敬1, 李雯艳1, 王叶同1, 王艳红1   

  1. 1.兰州大学护理学院,甘肃 兰州 730000;
    2.平凉市华亭市第二人民医院,甘肃 平凉 744100;
    3.甘肃省人民医院妇科,甘肃 兰州 730000
  • 收稿日期:2021-04-23 发布日期:2021-08-05
  • 通讯作者: 王艳红（1979-）,女,甘肃武威人,博士学历,副教授,硕士研究生导师。E-mail：yanhongwang@lzu.edu.cn
  • 作者简介:刘瑾（1997-）,女,甘肃庆阳人,本科学历,硕士研究生在读,护士。
  • 基金资助:
    国家自然科学基金项目（71804064）

Influence Factors of Cancer Recurrence Fear in Breast Cancer Patients：A Meta-analysis

LIU Jin1, LU Na2, ZHANG Feng-wa3, NIU Xiao-dan1, YUAN Rong-jing1, LI Wen-yan1, WANG Ye-tong1, WANG Yan-hong1   

  1. 1. School of Nursing, Lanzhou University, Lanzhou 730000, China;
    2. The Second Hospital of Huating City, Pingliang 744100,China;
    3. Dept. of Gynecology, Gansu Provincial People';s Hospital, Lanzhou 730000, China
  • Received:2021-04-23 Published:2021-08-05

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摘要： 目的 通过Meta分析,系统评价乳腺癌患者癌症复发恐惧的影响因素。方法 计算机检索PubMed、Web of Science、Cochrane Library、Embase、CINAHL Complete、CNKI、CBM、VIP、Wanfang 中外数据库,并辅助以人工检索,检索时限均从建库至2021年3月。由2位评价者独立筛选文献、提取资料和质量评价,采用R 4.0.2软件对符合纳入条件的文献进行Meta分析。结果 共纳入文献20篇,总样本量为6 374例,经Meta分析,影响因素合并r值分别为：年龄（r=-0.162,95%CI：-0.268~-0.057）;确诊时年龄（r=-0.313,95%CI：-0.362~-0.264）;家庭人均月收入（r=-0.174,95%CI：-0.229~-0.119）;肿瘤分期（r=0.243,95%CI：0.156~0.330）;负性情绪（r=0.609,95%CI: 0.494~0.724）;情绪表征（r=0.492,95%CI：0.359~0.624）;社会支持（r=-0.237,95%CI:-0.345~-0.128）;屈服（r=0.529,95%CI：0.386~0.674）。结论 人口学特征（年龄、确诊时年龄、家庭人均月收入）、疾病相关因素（肿瘤分期）、负性情绪、情绪表征、社会支持、应对方式（屈服）是乳腺癌患者癌症复发恐惧的主要影响因素,今后要加强对乳腺癌患者进行上述有关恐惧等心理现状的筛查,以期为乳腺癌患者提供个性化的干预,减少癌症复发恐惧的发生,降低患者已有的癌症复发恐惧水平。

关键词: 乳腺癌, 复发恐惧, 影响因素, Meta分析

Abstract: Objective To systematically evaluate the influence factors of fear of cancer recurrence in breast cancer patients through Meta-analysis. Methods We searched databases of PubMed, Web of Science, Cochrane Library, Embase, CINAHL Complete, CNKI, CBM, VIP, Wanfang by computer and with manual retrieval from the inception to March 2021. Two reviewers independently screened the literature, extracted the data, and evaluated the quality. R 4.0.2 software was used to perform meta-analysis on the literature that met the inclusion criteria. Results A total of 20 pieces of literature were included, with a total sample size of 6,374 cases. Through meta-analysis, the combined R-value of influence factors was age (r=-0.162, 95%CI: -0.268~-0.057); age at diagnosis (r=-0.313, 95%CI: -0.362~-0.264); per capita of family income (monthly)(r=-0.174,95%CI：-0.229~-0.119); tumor stage (r=0.243, 95%CI: 0.156~0.330); negative emotion (r=0.609, 95%CI: 0.494~0.724); emotional representation (r=0.492, 95%CI: 0.359~0.624);social support(r=-0.237, 95%CI: -0.345~-0.128); resignation（r=0.529, 95%CI：0.386~0.674). Conclusion Demography characteristics [age, age at diagnosis, per capita of family income (monthly)], disease-related factors (tumor stage), negative emotion, emotional representation, social support, coping style ( resignation) are the main influencing factors of fear of cancer recurrence in breast cancer patients. It is necessary to strengthen the screening of the above-mentioned psychological factors in breast cancer patients, so as to provide personalized intervention, and reduce the occurrence of fear of cancer recurrence and the level of fear of cancer recurrence in patients.

Key words: breast cancer, fear of recurrence, influencing factor, Meta-analysis

中图分类号: 

  • R473.73
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