以质量求发展,以服务铸品牌

护理学报 ›› 2024, Vol. 31 ›› Issue (8): 37-42.doi: 10.16460/j.issn1008-9969.2024.08.037

• 循证护理 • 上一篇    下一篇

早产儿初乳口腔免疫疗法的最佳证据总结

纪锐婷1, 林丹娜1, 刘小成2, 李婷婷3a, 谢映梅3a, 胡冰3b, 应文娟1   

  1. 1.汕头大学医学院,广东 汕头 515000;
    2.深圳市龙华区妇幼保健院 护理部,广东 深圳 518000;
    3.深圳市龙岗区妇幼保健院 a.新生儿科;b.护理部,广东 深圳 518000
  • 收稿日期:2023-12-11 出版日期:2024-04-25 发布日期:2024-05-08
  • 通讯作者: 应文娟(1964-),女,北京人,硕士,主任护师,副主任。E-mail: yingwenjuan@126.com
  • 作者简介:纪锐婷(1998-),女,广东汕头人,本科学历,硕士研究生在读。
  • 基金资助:
    深圳市龙岗区经济与科技发展专项资金(LGKCYLWS2020150)

Best evidence for colostrum as oral immune therapy in premature infants

JI Rui-ting1, LIN Dan-na1, LIU Xiao-cheng2, LI Ting-ting3a, XIE Ying-mei3a, HU Bing3b, YING Wen-juan1   

  1. 1. Medical College, Shantou University, Shantou 515000, China;
    2. Dept. of Nursing Administration, Longhua Maternity and Child Healthcare Hospital, Shenzhen 518000, China;
    3a. Dept. of Neonatology; 3b. Dept. of Nursing Administration, Longgang Maternity and Child Healthcare Hospital, Shenzhen 518000, China
  • Received:2023-12-11 Online:2024-04-25 Published:2024-05-08

摘要: 目的 检索、评价国内外早产儿行初乳口腔免疫疗法的证据,为开展早产儿初乳口腔免疫疗法提供临床实践依据。方法 根据“6S”证据模型,系统检索国内外数据库中关于早产儿运用初乳口腔免疫疗法的文献。由2名研究者独立对文献进行质量评价并提取整合证据。结果 共纳入11篇文献,其中指南3篇、专家共识1篇、临床决策1篇和系统评价6篇。从适宜对象、干预方法、初乳管理以及健康教育4个方面,共获得15条最佳证据。结论 本研究从适宜对象、干预方法、初乳管理及健康教育这4个方面归纳分析早产儿初乳口腔免疫疗法的最佳证据,医护人员可结合临床现有条件和患儿的实际情况开展初乳口腔免疫疗法,以促进患儿免疫系统的成熟及尽早达到出院标准。

关键词: 早产儿, 初乳口腔免疫疗法, 循证护理, 最佳证据

Abstract: Objective To retrieve and evaluate the best evidence for colostrum as oral immune therapy for premature infants at home and abroad, and to provide reference for clinical practice. Methods According to “6S” model, we systematically searched and collected the evidence regarding colostrum as oral immune therapy for premature infants. Two researchers evaluated the quality of the literature and extracted the data independently. Results Eleven pieces of literature were collected, including 3 guidelines, 1 evidence summary, 1 clinical decision, and 6 systematic reviews. Fifteen pieces of best evidence were obtained covering 4 aspects of suitable objects, intervention methods, management of colostrum and health education. Conclusion Colostrum as oral immune therapy could be delivered according to the best evidence. Clinical conditions and actual conditions of the preterm infants should be considered, so as to promote the maturity of the infants' immune system and reach the discharge standard as soon as possible.

Key words: premature infant, colostrum as oral immune therapy, evidence-based nursing, best evidence

中图分类号: 

  • R473.72
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