以质量求发展,以服务铸品牌

护理学报 ›› 2021, Vol. 28 ›› Issue (12): 21-26.doi: 10.16460/j.issn1008-9969.2021.12.021

• 循证护理 • 上一篇    下一篇

ICU成人危重症患者血糖管理的最佳证据总结

李菁菁a, 潘文彦b, 王晓容a, 赵金萍a, 蔡诗凝a   

  1. 复旦大学附属中山医院 a.外科监护室; b.护理部,上海 200032
  • 收稿日期:2020-11-12 出版日期:2021-06-25 发布日期:2021-07-06
  • 通讯作者: 潘文彦(1979-),女,上海人,本科学历,副主任护师,总护士长。E-mail:pan.wenyan@zs-hospital.sh.cn
  • 作者简介:李菁菁(1994-),女,上海人,本科学历,护师。
  • 基金资助:
    上海市科学技术委员会项目(20XD1420800); 复旦大学附属中山医院青年发展基金(2019ZSQN03); 复旦大学附属中山医院管理基金(2020ZSGL04)

Best Evidence Summary of Blood Glucose Management for ICU Adult Patients

LI Jing-jinga, PAN Wen-yanb, WANG Xiao-ronga, ZHAO Jin-Pinga, CAI Shi-ninga   

  1. 1. Surgical Intensive Care Unit;
    2. Dept. of Nursing Administration, Zhongshan Hospital, Fudan University, Shanghai 200032, China
  • Received:2020-11-12 Online:2021-06-25 Published:2021-07-06

摘要: 目的 总结ICU成人危重症患者血糖管理的最佳证据,为临床实践提供参考。方法 检索Up To Date、JBI循证卫生保健中心数据库、BMJ Best Practice、Cochrane Library、国际指南协作网(Guidelines International Network, GIN)、英国国家卫生与临床优化研究所(National Institute for Health and Care Excellence, NICE)、苏格兰院际指南网(Scottish Intercollegiate Guidelines Network, SIGN)、美国国立指南库(National Guideline Clearinghouse, NGC)、加拿大安大略注册护士协会(Registered Nurses Association of Ontario, RNAO)、美国危重症学会(Society of Critical Care Medicine, SCCM)、PubMed、EMBASE、Springer、中国知网、万方、维普网中所有ICU成人危重症患者血糖管理相关的临床决策、指南、证据总结、专家共识。通过文献质量评价,对符合质量标准的文献进行证据提取。结果 共纳入11篇文献,其中1篇临床决策、4篇指南、4篇专家共识、2篇证据总结。形成的最佳证据包括血糖控制目标、血糖监测、高血糖的管理、低血糖的管理、脓毒症患者血糖管理和质量控制6个方面,共19条证据。结论 ICU血糖管理对危重症患者有重要意义,通过总结最佳证据,可为临床工作提供参考。

关键词: 危重症, 血糖管理, 证据总结

Abstract: Objective To summarize the best evidence for blood glucose management in ICU adult patients to provide reference for clinical practice. Methods We searched Up To Date, JBI, BMJ Best Practice, Cochrane Library, Guidelines International Network(GIN), National Institute for Health and Care Excellence,(NICE), Scottish Intercollegiate Guidelines Network(SIGN), National Guideline Clearinghouse(NGC), Registered Nurses Association of Ontario(RNAO), Society of Critical Care Medicine(SCCM), PubMed, EMBASE, Springer, CNKI, Wangfang and VIP to collect clinical decisions, guidelines, evidence summaries, expert consensus related to blood glucose management of adult patients in ICU. Through literature quality evaluation, evidence was extracted from the literature that met the quality standards. Results A total of 11 articles were selected: 1 clinical decision, 4 guidelines, 4 expert consensuses and 2 evidence summaries. Nineteen pieces of best evidence were obtained including 7 aspects of blood glucose control goals, blood glucose monitoring, hyperglycemia management,hypoglycemia management, sepsis patient management and quality control. Conclusion Blood glucose management plays a crucial role in ICU and best evidence summary of blood glucose management provides reference for clinical practice.

Key words: critical ill, blood glucose management, evidence summary

中图分类号: 

  • R473
[1] 唐红玉, 王吉平. 成年危重病人血糖管理相关临床实践指南现况及内容分析[J]. 护理研究, 2018,32(4):499-505.DOI:10.3969/j.issn.1009-6493.2018.04.001.
[2] 赵玲, 陶志敏. 急危重症患者快速血糖测定的临床意义探讨[J]. 中国实用医药, 2008(33):71-72.DOI:10.3969/j.issn.1671-038X.2014.04.13.
[3] 潘文彦, 赵慧华, 钟鸣, 等. 信息化血糖采集系统在ICU患者血糖管理中的应用[J].护士进修杂志,2017,32(17):1575-1577.DOI:10.16821/j.cnki.hsjx.2017.17.011.
[4] Lanspa MJ, Dickerson J, Morris AH, et al.Coefficient of Glucose Variation Is Independently Associated with Mortality in Critically Ill Patients Receiving Intravenous Insulin[J]. Crit Care, 2014,18(2):R86. DOI:10.1186/cc13851.
[5] Dicenso A, Bayley L, Haynes RB.Accessing Pre-appraised Evidence: Fine Tuning 5S Model into the 6S Model[J]. Evid Based Nurs,2009,151(4):99-101. DOI:10.1136/ebn.12.4.99-b.
[6] 谢利民, 王文岳. 《临床指南研究与评价系统Ⅱ》简介[J]. 中西医结合学报,2012,10(2):160-165.DOI:10.3736/jcim20120206.
[7] 谭静, 韩江全, 胡春婷, 等. 脑卒中后抑郁管理的最佳证据总结[J].护理学报,2020,27(23):42-48.DOI:10.16460/j.issn1008-9969.2020.23.042.
[8] 王焕焕, 程湘玮, 王培红, 等. 妊娠期糖尿病产妇分娩新生儿低血糖管理的最佳证据总结[J]. 护理学报,2020,27(3):31-36.DOI:10.16460/j.issn1008-9969.2020.03.031.
[9] 胡雁,郝玉芳. 循证护理学[M].北京: 人民卫生出版社, 2012:77-78.
[10] 周英凤, 顾莺, 胡雁, 等. JBI 循证卫生保健中心关于不同类型研究的质量评价工具——干预性研究的质量评价(一)[J]. 护士进修杂志,2018,33(1):24-26.DOI:10.16821/j.cnki.hsjx.2018.02.006.
[11] 顾莺, 张慧文, 周英凤, 等. JBI循证卫生保健中心关于不同类型研究的质量评价工具——系统评价的方法学质量评价[J]. 护士进修杂志,2018,33(8):701-703.DOI:10.16821/j.cnki.hsjx.2018.08.008.
[12] 王春青, 胡雁. JBI证据预分级及证据推荐级别系统(2014版)[J]. 护士进修杂志,2015,30(11):964-967.
[13] Jacobi J, Bircher N, Krinsley J, et al.Guidelines for the Use of an Insulin Infusion for The Management of Hyperglycemia in Critically Ill Patients[J]. Crit Care Med, 2012, 40(12):3251-3276.DOI:10.1097/CCM.0b013e3182653269.
[14] Rhodes A, Evans LE, Alhazzani W, et al.Surviving Sepsis Campaign:International Guidelines for Management of Sepsis and Septic Shock: 2016[J]. Crit Care Med, 2017,45(3):486-552. DOI:10.1007/s00134-017-4683-6.
[15] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2017年版)[J]. 中国实用内科杂志,2018,34(4):292-344.DOI:10.19538/j.nk2018040108.
[16] 中国医师协会急诊医师分会, 中国研究型医院学会休克与脓毒症专业委员会. 中国脓毒症/脓毒性休克急诊治疗指南(2018)[J]. 临床急诊杂志, 2018,19(9):567-588.DOI: 10.13201/j.issn.1009-5918.2018.09.001.
[17] Moghissi ES, Korytkowski MT, DiNardo M, et al. American Association of Clinical Endocrinologists and American Diabetes Association Consensus Statement on Inpatient Glycemic Control[J]. Diabetes Care,2009,32(6):1119-1131. DOI:10.2337/dc09-9029.
[18] Ichai C, Preiser JC, Societe Francaise dAR, et al. International Recommendations for Glucose Control in Adult Non Diabetic Critically Ill Patients[J]. Crit Care, 2010,14(5):R166. DOI:10.1186/cc9258.
[19] Finfer S, Wernerman J, Preiser JC, et al.Clinical Review: Consensus Recommendations on Measurement of Blood Glucose and Reporting Glycemic Control in Critically Ill Adults[J]. Crit Care,2013,17(3):229.DOI:10.1186/cc12537.
[20] Mukherjee JJ, Chatterjee PS, Saikia M, et al.Consensus Recommendations for the Management of Hyperglycaemia in Critically Ill Patients in the Indian Setting[J]. J Assoc Physicians India,2014,62(7 Suppl):16-25.
[21] UpToDate. Glycemic Control and Intensive Insulin Therapy in Critical Illness[EB/OL].[2020-06-26]. https://www.uptodate.cn/contents/glycemic-control-and-intensive-insulin-therapy-in-critical-illness?search=Glycemic%20control%20and%20intensive%20insulin%20therapy%20in%20critical%20illness&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1.
[22] Jayasekara R.Intensive Care Unit Insulin Infusion: Blood Glucose Monitoring (Adults).[EB/OL].[2020-06-30].https://ovidsp.dc2.ovid.com/ovid-b/ovidweb.cgi?&S=GMGLFPHJOIEBDLKDJPPJKFBHIIECAA00&Link+Set=S.sh.39%7c1%7csl_190.
[23] Slade S.Critically Ill Patients: Glycemic Control.[EB/OL].[2020-06-30]. https://ovidsp.dc2.ovid.com/ovid-b/ovidweb.cgi?&S=GMGLFPHJOIEBDLKDJPPJKFBHIIECAA00&Link+Set=S.sh.43%7c1%7csl_190.
[24] Meijering S, Corstjens AM, Tulleken JE, et al.Towards a Feasible Algorithm for Tight Glycaemic Control in Critically Ill Patients: A Systematic Review of the Literature[J]. Crit Care, 2006,10(1):R19. DOI:10.1186/cc3981.
[25] Preiser JC, Devos P, Ruiz-Santana S, et al.A Prospective Randomised Multi-centre Controlled Trial on Tight Glucose Control by Intensive Insulin Therapy in Adult Intensive Care Units: The Glucontrol Study[J]. Intensive Care Med, 2009,35(10):1738-1748. DOI:10.1007/s00134-009-1585-2.
[26] Finfer S, Blair D, Bellomo R, et al.Intensive Versus Conventional Glucose Control in Critically Ill Patients[J]. N Engl J Med,2009,360(13):1283-1297.DOI:10.1056/NEJMoa0810625.
[27] Arabi YM, Dabbagh OC, Tamim HM, et al.Intensive Versus Conventional Insulin Therapy: A Randomized Controlled Trial in Medical and Surgical Critically Ill Patients[J]. Crit Care Med,2008,36(12):3190-3197. DOI:10.1097/CCM.0b013e31818f21aa.
[28] Critchell CD, Savarese V, Callahan A, et al.Accuracy of Bedside Capillary Blood Glucose Measurements in Critically Ill Patients[J]. Intensive Care Med, 2007,33(12):2079-2084. DOI:10.1007/s00134-007-0835-4.
[29] Kanji S, Buffie J, Hutton B, et al.Reliability of Point-of-care Testing for Glucose Measurement in Critically Ill Adults[J]. Crit Care Med, 2005,33(12):2778-2785. DOI: 10.1097/01.ccm.0000189939.10881.60.
[30] Li X, Ma YQ, Chen TL,et al.Bedside Blood Glucose Monitoring in Critically Ill Patients: Comparison between Arterial and Capillary Glucose[J]. Am J Med Sci, 2017,354(5):458-461. DOI: 10.1016/j.amjms.2017.05.005.
[31] Van den Berghe G, Wilmer A, Hermans G, et al. Intensive Insulin Therapy in The Medical ICU[J]. N Engl J Med,2006,354(5):449-461. DOI:10.1056/NEJMoa052521.
[32] Vriesendorp TM, van Santen S, DeVries JH, et al. Predisposing Factors for Hypoglycemia in the Intensive Care Unit[J]. Crit Care Med,2006,34(1):96-101. DOI:10.1097/01.ccm.0000194536.89694.06.
[33] Scalea TM, Bochicchio GV, Bochicchio KM, et al.Tight Glycemic Control in Critically Injured Trauma Patients[J]. Ann Surg, 2007, 246(4):605-612.DOI:10.1097/SLA.0b013e318155a789.
[34] Juneja R, Roudebush CP, Nasraway SA, et al.Computerized Intensive Insulin Dosing Can Mitigate Hypoglycemia and Achieve Tight Glycemic Control When Glucose Measurement Is Performed Frequently and on Time[J].Crit Care, 2009,13(5):R163. DOI:10.1186/cc8129.
[1] 崔朝妹, 刘静, 庄欣, 杜娟, 董春晖. ICU成人患者有创机械通气撤机的最佳证据总结[J]. 护理学报, 2021, 28(6): 27-32.
[2] 曲畅, 郭海玲, 魏宇, 李学靖, 张小艳, 丛雪, 王斗, 晏利姣, 郝玉芳. 维持性血液透析后疲乏管理最佳证据总结[J]. 护理学报, 2021, 28(5): 43-48.
[3] 陆涵, 赵媛, 朱晓丽, 林惠仙, 史婷婷. 基于改良早期预警评分护送方案在急危重症患者院内转运中应用效果的Meta分析[J]. 护理学报, 2021, 28(4): 19-25.
[4] 严玉娇, 丁娟, 刘晁含, 付沫, 王虹. 成人危重症患者气道管理的最佳证据总结[J]. 护理学报, 2021, 28(3): 39-45.
[5] 张玉坤, 王钰炜, 王飒, 闫丹萍, 陈水红. 成人ICU患者疼痛管理的最佳证据总结[J]. 护理学报, 2021, 28(11): 40-45.
[6] 吴溢涛, 王晓容, 潘文彦, 李菁菁, 钱晨. 分级色块管理方案在危重症患者院内转运中的应用及效果评价[J]. 护理学报, 2021, 28(10): 17-23.
[7] 叶丽, 黄厚强, 郭声敏, 刘琰, 郑思琳. 脑卒中后神经源性膀胱管理的最佳证据总结[J]. 护理学报, 2021, 28(10): 40-44.
[8] 张雯澜, 傅丽娟, 陆华, 王莹, 任宏, 张建. 肺部超声评分联合氧合功能指标对机械通气患儿撤机结局的预测分析[J]. 护理学报, 2021, 28(1): 64-68.
[9] 章明阳, 杜李百合, 罗小平, 章文军, 梁爱群, 常后婵. 术前患者预保温的最佳证据总结[J]. 护理学报, 2020, 27(6): 17-22.
[10] 李曼, 薛秀娟. 山东省50家二级及以上医院1 014名ICU护士对危重患者肠内喂养障碍的现状分析[J]. 护理学报, 2020, 27(5): 39-41.
[11] 张煜, 张春艳, 金玉, 王淑芹, 董亮, 万娜, 贾燕瑞, 高凤莉. 内科危重症患者深静脉血栓预防审查指标的制定及障碍因素分析[J]. 护理学报, 2020, 27(4): 37-41.
[12] 黄厚强, 郭声敏, 叶丽, 郑思琳. 脑卒中后偏瘫性肩痛预防及管理的最佳证据总结[J]. 护理学报, 2020, 27(23): 37-41.
[13] 王兆北, 陈玲, 李红, 石磊, 李永宁, 陈义刚. 肝移植患者术后早期活动管理的证据总结[J]. 护理学报, 2020, 27(21): 46-50.
[14] 田志军, 俞晓梅. 自制体外膜肺氧合转运架的研制与应用[J]. 护理学报, 2020, 27(16): 77-78.
[15] 陈晓宇, 黄洁微, 李艳萍, 周佩如. 危重症患者指尖血糖监测结果的影响因素及对策研究进展[J]. 护理学报, 2020, 27(15): 25-28.
Viewed
Full text


Abstract

Cited

  Shared   
[1] 杜荣欣, 张晓红, 刘艳华, 张芳, 徐娟. 永久性肠造口患者延续性护理需求量表的编制及信效度检验[J]. 护理学报, 2020, 27(14): 1 -4 .
[2] 王金艳, 吴丽萍, 邢丽莉, 龚晶晶. 297名助产士共情能力调查分析[J]. 护理学报, 2020, 27(14): 5 -8 .
[3] 李姮, 石美霞, 郭倩楠. 山西省1546名养老护理员培训认同感现状及影响因素分析[J]. 护理学报, 2020, 27(14): 9 -12 .
[4] 宋杰, 曲桂玉, 张玉珍, 侯姗姗, 赵春玲. 护理学专业骨干教师胜任力评价的量化指标体系构建[J]. 护理学报, 2020, 27(14): 13 -16 .
[5] 李建云, 谢小朋, 沈美玲, 赵振华, 黄一丹. 两站式入院流程在心内科的应用效果观察[J]. 护理学报, 2020, 27(14): 17 -19 .
[6] 卢婷, 应燕萍, 徐谊, 袁丽秀, 周琼, 黄彪进. 握力与NRS 2002在恶性肿瘤患者营养风险筛查中的对比研究[J]. 护理学报, 2021, 28(9): 1 -4 .
[7] 赵广芳, 邢爱红, 代玲玉, 陈浩, 吴玉玲, 赵红乐, 张淑香. 山东省5所高职院校护生老年照护择业动机现状及影响因素分析[J]. 护理学报, 2021, 28(10): 1 -6 .
[8] 刘丹阳, 艾军, 李丹, 廖生武, 朱清瑶, 龚妮容, 张婷婷, 张广清. 规律门诊随访对腹膜透析患者高血压控制率及相关疾病转归影响的回顾性分析[J]. 护理学报, 2021, 28(10): 11 -16 .
[9] 牛晓丹, 张静, 郭静波, 阮海慧, 迟俊婷, 陶红霞, 王艳红. 糖尿病患者衰弱危险因素的Meta分析[J]. 护理学报, 2021, 28(11): 1 -6 .
[10] 陈丽玲, 周春兰, 吴艳妮, 赵慧慧. 临床护士循证实践培训体系的构建[J]. 护理学报, 2021, 28(11): 7 -11 .