以质量求发展,以服务铸品牌

护理学报 ›› 2018, Vol. 25 ›› Issue (21): 47-50.doi: 10.16460/j.issn1008-9969.2018.21.047

• 临床护理 • 上一篇    下一篇

飞行员泌尿系结石与尿液成分关系的病例对照研究

张海红1, 孙玉梅2, 崔亮1, 张丽洁2, 苏叶2, 邢鹏博2, 高江平3   

  1. 1.民航总医院 泌尿外科,北京 100123;
    2.北京大学 护理学院,北京 100191;
    3.中国人民解放军总医院,北京 100853
  • 收稿日期:2018-06-18 发布日期:2020-07-08
  • 通讯作者: 孙玉梅(1969-),女,辽宁朝阳人,硕士,副教授,硕士研究生导师。
  • 作者简介:张海红(1982-),女,山东潍坊人,硕士,主管护师,护士长。
  • 基金资助:
    国家自然科学基金(51375494)

Case-control Study on Relationship between Urine Components and Urinary Calculus in Pilots

ZHANG Hai-hong1, SUN Yu-mei2, CUI Liang1, Zhang Li-jie2, SU Ye2, XING Peng-bo2, GAO Jiang-ping3   

  1. 1. Dept. of Urinary Surgery, Civil Aviation General Hospital, Beijing 100123, China;
    2. School of Nursing, Peking University, Beijing 100191, China;
    3. General Hospital of PLA, Beijing 100853, China
  • Received:2018-06-18 Published:2020-07-08

摘要: 目的 探讨飞行员泌尿系结石发生与尿液成分的关系。方法 采用1∶3病例对照研究,对2017年3—12月在某三级综合医院泌尿科住院的64例结石飞行员和同期192例健康飞行员的晨尿进行成分分析。结果 对2组飞行员的尿液成分进行多因素Logistic回归分析发现,尿钙、磷、钠是结石形成的危险因素,其OR值分别为4.31、1.20和1.04;尿氯、尿镁是结石的保护性因素,其OR值为0.96和0.95。结论 定期监测飞行员晨尿中钙、磷、钠、氯、镁,及早发现结石的危险因素,尽早对高危飞行员进行生活方式的干预,可能会降低结石的发生率。

关键词: 飞行员, 泌尿系结石, 尿液成分, 危险因素, 病例对照

Abstract: Objective To explore the relationships between urine components and urinary calculus in pilots. Methods A 1:3 case-control study was carried out. From March to December 2017, 64 hospitalized pilots with calculus in a tertiary general hospital and during the same period, 192 cases of healthy pilots were involved in the study and their morning urine components were analyzed. Results Multivariate logistic regression analysis of the urine composition of the two groups found that urinary calcium, phosphorus and sodium were risk factors for calculus formation, and OR value was 4.31, 1.20 and 1.04 respectively. Urinary chloride and magnesium were protective factors for calculi, with an OR value of 0.96 and 0.95 respectively. Conclusion Regular monitoring of urinary calcium, phosphorus, sodium, chloride and magnesium in early morning urine, early detection of risk factors for stones, and early intervention in the lifestyle of high-risk pilots may reduce the incidence of calculus.

Key words: the pilot, urinary calculus, urine composition, risk factor, case-control

中图分类号: 

  • R473.6
[1] 梁谷米,余清平. 飞行人员尿石症临床特点和医学鉴定[J]. 中华航空航天医学杂志, 2006(3):222-224. DOI:10.3760/cma.j.issn.1007-6239.2006.03.013.
[2] 郑杰. 飞行人员泌尿系结石的病因学研究[D]. 合肥:安徽医科大学, 2012.
[3] 杜鹏,王若永,穆慧玲,等. 高性能战斗机飞行员膳食调查与分析: 中国营养学会第十次特殊营养学术会议[C].温州:中国营养学会特殊营养分会, 2017.
[4] Bird V Y, Khan S R.How Do Stones Form? Is Unification of Theories on Stone Formation Possible?[J]. Arch Esp Urol, 2017,70(1):12-27.
[5] 孙振球,徐勇勇. 医学统计学[M].北京:人民卫生出版社, 2016:244-255.
[6] Green W, Ratan H.Molecular Mechanisms of Urolithiasis[J]. Urology,2013,81(4):701-704.DOI:10.1016/j.Urology.2012.12.039.
[7] Skolarikos A, Straub M, Knoll T, et al.Metabolic Evaluation and Recurrence Prevention for Urinary Stone Patients: Eau Guidelines[J]. Eur Urol, 2015,67(4):750-763.DOI:10.1016/j.Eururo.2014.10.029.
[8] Parks J H, Goldfisher E, Asplin J R, et al.A Single 24-Hour Urine Collection is Inadequate for the Medical Evaluation of Nephrolithiasis[J]. J Urol, 2002,167(4):1607-1612. [9] Ogawa Y, Yonou H, Hokama S, et al. Urinary Saturation and Risk Factors for Calcium Oxalate Stone Disease Based on Spot And 24-hour Urine Specimens[J]. Front Biosci, 2003,8:a167-a176.
[10] Han H, Segal A M, Seifter J L, et al.Nutritional Management of Kidney Stones (Nephrolithiasis)[J]. Clin Nutr Res, 2015,4(3):137-152.DOI:10.7762/Cnr.2015.4.3.137.
[11] Dent C E, Sutor D J.Presence or Absence of Inhibitor of Calcium-Oxalate Crystal Growth in Urine of Normals and of Stoneformers[J]. Lancet, 1971,2(7728):775-778.
[12] 曹秋生,曹欣,黄士杰,等. 尿液成分对草酸钙结石的影响[J]. 现代泌尿外科杂志, 2007(6):366-367.DOI:10.3969/j.Issn.1009-8291.2007.06.006.
[13] Eisner B H, Eisenberg M L, Stoller M L.Relationship Between Body Mass Index and Quantitative 24-hour Urine Chemistries in Patients with Nephrolithiasis[J].Urology, 2010,75(6):1289-1293. DOI:10.1016/j.Urology.2009.09.024.
[14] Al-Hayek S, Schwen Z R, Jackman S V, et al.The Impact of Obesity on Urine Composition and Nephrolithiasis Management[J]. J Endourol, 2013,27(3):379-383. DOI:10.1089/End.2012.0275.
[15] Khand F D, Ansari A F, Khand T U, et al.Is Hypocitraturia Associated with Phosphaturia--a Potential Cause of Calcium Urolithiasis in First-time Stone Formers[J]. J Pak Med Assoc, 1994,44(8):179-181.
[16] Gyawali P R, Joshi B R, Gurung C K.Correlation of Calcium, Phosphorus, Uric Acid and Magnesium Level In Serum and 24 Hours Urine of Patients With Urolithiasis[J]. Kathmandu Univ Med J (Kumj), 2011,9(34):54-56. DOI:10.3126/Kumj.v9i2.6289.
[17] Wikstrom B, Backman U, Danielson B G, et al.Phosphate Metabolism in Renal Stone Formers. (I): Indices of Phosphate Handling in Calcium Stone Patients and Healthy Subjects[J]. Scand J Urol Nephrol Suppl, 1981,61:1-18.
[18] Ha Y S, Tchey D U, Kang H W, et al.Phosphaturia As a Promising Predictor of Recurrent Stone Formation in Patients with Urolithiasis[J]. Korean J Urol, 2010,51(1):54-59.DOI:10.4111/Kju.2010.51.1.54.
[19] Kim Y J, Kim T H, Yun S J, et al.Renal Phosphate Control As a Reliable Predictive Factor of Stone Recurrence[J]. J Urol, 2009,181(6):2566-2572, 2572. DOI: 10.1016/j.Juro.2009.01.101.
[20] Nouvenne A, Meschi T, Prati B, et al.Effects of a Low-salt Diet on Idiopathic Hypercalciuria in Calcium-Oxalate Stone Formers: A 3-Mo Randomized Controlled Trial[J]. Am J Clin Nutr, 2010,91(3):565-570.DOI:10.3945/Ajcn.2009.28614.
[21] Eisner B H, Eisenberg M L, Stoller M L.Impact of Urine Sodium on Urine Risk Factors for Calcium Oxalate Nephrolithiasis[J]. J Urol,2009,182(5):2330-2333.DOI:10.1016/j.Juro.2009.07.014.
[22] Bibilash B S, Vijay A, Fazil M Y.Stone Composition and Metabolic Status[J]. Urol Res, 2010,38(3):211-213. DOI:10.1007/s00240-009-0229-x.
[23] Reungjui S, Prasongwatana V, Premgamone A, et al.Magnesium Status of Patients With Renal Stones and its Effect on Urinary Citrate Excretion[J]. Bju Int, 2002,90(7):635-639.
[24] 蒲金赟,周建华. 氯离子通道与肾脏病[J]. 临床儿科杂志, 2016(2):150-153. DOI:10.3969/j.Issn.1000-3606.2016.02.017.
[1] 田婷, 黄锐娜, 戚熠, 周亚娟, 韩慧, 刘婉君, 贺海霞, 吴小婉. 肿瘤患者PICC置管相关静脉血栓形成危险因素Meta分析[J]. 护理学报, 2019, 26(11): 49-54.
[2] 李如雪, 林平, 高雪琴, 王旖旎. A型行为模式和D型人格概述及与冠心病的关系研究进展[J]. 护理学报, 2018, 25(22): 23-26.
[3] 李真, 曹晶, 李佳倩, 吴欣娟. 卒中后谵妄危险因素的Meta分析[J]. 护理学报, 2018, 25(22): 38-43.
[4] 熊沙沙,彭历,彭丽娟. 癌症患者发生癌性爆发痛的现状及影响因素分析[J]. 护理学报, 2017, 24(8): 26-29.
[5] 黄维健,曲华. 手术患者压疮危险因素评估指标体系的构建[J]. 护理学报, 2017, 24(3): 9-13.
[6] 梁瑞晨,杨昌美,韩杰,张申洪,邓文雪,骆雪英. 泌尿外科腰麻微创手术患者术中低体温发生情况及其影响因素分析[J]. 护理学报, 2017, 24(24): 5-8.
[7] 曹小彤,徐翠荣,王静静. 慢性心力衰竭患者生活质量影响因素的病例对照研究[J]. 护理学报, 2017, 24(23): 5-8.
[8] 霍婉君,刘荣敏,冯素云,曾繁端,熊小玲. 2007-2016年我国压疮发生危险因素研究的文献计量分析[J]. 护理学报, 2017, 24(20): 14-16.
[9] 朱远,王燕君,张爱霞,徐桂华. 头位阴道分娩会阴切开影响因素Logistic回归分析[J]. 护理学报, 2017, 24(16): 10-13.
[10] 彭淑华. 硬膜外血肿清除术患者获得性吞咽障碍发生危险因素的病例对照研究[J]. 护理学报, 2017, 24(16): 43-45.
[11] 张频,宋瑜,奚燕. 晚期胰腺癌患者介入术后血栓影响因素病例对照研究[J]. 护理学报, 2017, 24(16): 31-33.
[12] 赵春莉,陶惠. 经皮冠状动脉介入治疗患者冠心病危险因素2年随访结果分析[J]. 护理学报, 2016, 23(8): 40-42.
[13] 田义华,赵庆华,肖明朝,陈洁,唐永利. 老年住院患者安全危险因素评估量表的编制及信效度检验[J]. 护理学报, 2016, 23(7): 54-56.
[14] 邓玉玲,严谨,王秀华,杨娉婷,易琦峰,林艳辉,杨艳,陈志恒. 长沙市46000名职工血脂状况调查与影响因素分析[J]. 护理学报, 2016, 23(6): 41-44.
[15] 李杭霏,苏向妮,徐莎莎,尼春萍,王静,王文辰. 社区认知障碍老年人生活质量调查及影响因素分析[J]. 护理学报, 2016, 23(4): 41-43.
Viewed
Full text


Abstract

Cited

  Shared   
[1] 张冬妮,刘永军. 老年人自我健康管理综合策略研究进展[J]. 护理学报, 2013, 20(11): 25 -27 .
[2] 王新,李桂友,邓美莲. 1095例孕妇盆腔脏器脱垂影响因素分析[J]. 护理学报, 2013, 20(11): 28 -30 .
[3] 李媛, 张瑞, 卢艳艳, 宁佩, 李雪, 孟庆慧. 师生不同视角下危重症护理硕士专业学位研究生学习方法研究[J]. 护理学报, 2020, 27(11): 1 -5 .
[4] 赵迪, 赵梦璐, 王娜, 付明晶, 梁凤, 张伟, 王爱敏. 青岛市592名社区老年人社会隔离现状及影响因素研究[J]. 护理学报, 2020, 27(11): 6 -10 .
[5] 高莹, 吴玉娥, 张建荣, 崔鑫浩, 陈淑玲, 叶丽芳, 杜秀珍. 基于循证构建轻症急性胰腺炎患者早期经口进食时机评估及管理方案[J]. 护理学报, 2020, 27(11): 11 -15 .
[6] 谢延真, 李壮苗, 张佳宇, 纪秋露, 吴宇欣. 灸法治疗脑卒中后偏瘫的文献计量学分析[J]. 护理学报, 2020, 27(11): 16 -20 .
[7] 练巧兰, 欧阳红莲. 成人ICU患者探视管理研究进展[J]. 护理学报, 2020, 27(11): 21 -25 .
[8] 张爱琴, 陈俊杉, 余金甜. ICU患者谵妄非药物管理相关指南的系统评价[J]. 护理学报, 2020, 27(11): 26 -32 .
[9] 叶冬婷, 张沁莲, 景霜, 郭佳, 邢雁芬. 家属对ICU患者转出体验的Meta整合[J]. 护理学报, 2020, 27(11): 33 -39 .
[10] 刘敏, 刘安诺, 吴德全, 高宇, 陈国红, 朱桂月, 张萌, 马雯, 丁翠路. 运动干预对2型糖尿病老年患者步行功能影响的Meta分析[J]. 护理学报, 2020, 27(11): 40 -45 .