Improving the innovation capacity is very important for the development of enterprise groups. One of the most conspicuous problems faced by Chinese enterprise groups during the innovation process is that the synergy and collaboration between subsidiary companies inside the enterprise groups are ignores, and the innovation performances are limited. Were analyzed three aspects: (1) The key factors of synergetic innovation in enterprise group, (2) the relationship between the key factors of synergetic innovation and synergetic effect, (3) the relationship between synergetic effect and innovation performance. Synergetic innovation management inside enterprise groups were also studied theoretically and empirically.