Abstract: Objective To investigate the status quo of negative social expectation of nasopharyngeal carcinoma patients undergoing concurrent radiotherapy and chemotherapy, and to analyze its influencing factors. Methods With convenient sampling, 200 patients with nasopharyngeal carcinoma hospitalized in the radiotherapy department of the First Affiliated Hospital of Guangxi Medical University were selected from January to June 2021, and were surveyed by using General Information Questionnaire, Cancer-related Negative Social Expectation Scale, Perceived Social Support Scale, and the Acceptance of Illness Scale. Multiple linear regression was used to analyze the influencing factors of negative social expectation. Results The total score of negative social expectation in this group was 18.00±5.64. Multiple linear regression analysis showed that perceived social support (B=-0.354,P<0.001), clinical stage (B=1.108,P=0.019), disease acceptance (B=-0.350,P<0.001), number of symptoms (B=0.918,P=0.009), number of radiotherapy for nasopharyngeal carcinoma (B=1.246,P<0.001), and without accompanying and accompanied by nursing workers (B=2.831,1.686;P<0.001,P=0.026) entered the regression equation (P<0.05), which explained 60.8% of the total variation. Conclusion The score of negative social expectation of the patients with nasopharyngeal carcinoma undergoing concurrent radiotherapy and chemotherapy is at the middle level. Perceived social support, clinical stage, disease acceptance, number of symptoms, radiotherapy frequency of nasopharyngeal carcinoma, without accompanying and accompanied by nursing workers are the influencing factors of the negative social expectation. Timely assessment and intervention and clinical nursing plan for negative social expectations are conducive to reducing patients' negative social expectation.

Key words: nasopharyngeal carcinoma, concurrent radiotherapy and chemotherapy, negative social expectations