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Journal of Nursing ›› 2019, Vol. 26 ›› Issue (23): 6-10.doi: 10.16460/j.issn1008-9969.2019.23.006

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Changes of Symptom Clusters among Nasopharyngeal Carcinoma Patients undergoing Concurrent Chemoradiotherapy: A Longitudinal Study

ZHANG Na1, SONG Jin-xia2, WANG Hong-qiao2, ZHOU Jing2, JIN Yong-long2, WANG Yuan-yuan2, SUN Hui-hui1   

  1. 1. School of Nursing, Qingdao University, Qingdao 266100, China;
    2. Affiliated Hospital, Qingdao University, Qingdao 266003,China
  • Received:2019-07-31 Published:2020-07-27

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Abstract: Objective To explore the types and dynamic changes of symptom clusters in nasopharyngeal carcinoma patients with concurrent chemoradiotherapy during different treatment phases and to provide reference for extended symptom management. Methods With convenient sampling method, 118 nasopharyngeal carcinoma patients with concurrent chemoradiotherapy were recruited. The MDASI- H&N was used to collect the data at the end of 2, 4, 6 weeks after radiotherapy (T1, T2, T3 respectively), and 1 month after radiotherapy (T4). Symptom clusters were constructed using exploratory factor analysis. Results Four symptom clusters were extracted, in which fatigue-sleep-emotion symptom clusters and oral mucosal symptom clusters persisted in T1-T4; vocal-dysphagia symptom clusters in T2-T4, and gastrointestinal symptom clusters only existed in T2-T3. The severity of symptom clusters at different time points was statistically significant（P<0.05）. Conclusion It is necessary to pay more attention to the dynamic changes of symptom clusters in nasopharyngeal carcinoma patients with concurrent chemoradiotherapy and take targeted interventions based on internal symptoms at each time point.

Key words: nasopharyngeal carcinoma, concurrent chemoradiotherapy, symptom clusters, longitudinal study

CLC Number: 

  • R473.76
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