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Journal of Nursing ›› 2020, Vol. 27 ›› Issue (23): 53-57.doi: 10.16460/j.issn1008-9969.2020.23.053

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Case-control Study on Risk Factors of Infectious Diarrhea in Hospitalized Children with Acute Leukemia

CHEN Lin, GE Zheng-zheng, ZHANG Xiao-yan   

  1. Dept. of Hematology and Oncology,Shanghai Children's Medical Center,School of Medicine,Shanghai Jiaotong University,Shanghai 200127,China
  • Received:2020-07-17 Online:2020-12-10 Published:2021-01-15

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Abstract: Objective To explore the risk factors for infectious diarrhea in hospitalized children with acute leukemia.Methods We conducted a retrospective analysis of the data of hospitalized pediatric patients with infectious diarrhea in a specialized pediatric hospital in Shanghai from July 2017 to July 2018,and children were divided into infectious diarrhea group (n=48),and control group without infectious diarrhea(n=1,293).Binary logistic regression analysis was carried out to explore the risk factors of infectious diarrhea.Results There were 48 cases of infectious diarrhea in 1,341 patients with acute leukemia,with an incidence rate of 3.58%.Binary logistic regression analysis showed that anthracyclines,cytarabine,glucocorticoids,blood transfusion,admitting in summer and non-solid food were risk factors of infectious diarrhea in hospitalized children with acute leukemia (P<0.05).And the results also showed that the higher height was the protective factor for infectious diarrhea in leukemia patients(P<0.05).Conclusion Hospitalized pediatric patients with anthracyclines,cytarabine or glucocorticoids or blood transfusion,admitting in summer,or having non-solid food would be at higher risk of infectious diarrhea but those with higher height have the lower risk of infectious diarrhea.Early assessment of risk factors,health instructions,and preventions should be emphasized to decrease the incidences of infectious diarrhea.

Key words: acute leukemia, infectious diarrhea, protective factor, risk factor

CLC Number: 

  • R473.72
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