Based on the technological-economic paradigm theory framework, this study constructs a relational model between artificial intelligence (AI) and the “lock-in effect”in enterprise suppliers, and explores the mechanisms from the perspective of advantages of the information and competition. On this basis, an empirical test is conducted using samples of non-financial A-share listed companies in China from 2007 to 2023. The results show that AI can effectively mitigate the “lock-in effect”of enterprise supplier. After fully considering the issues of endogeneity and robustness, the results remain valid. AI alleviates the supplier “lock-in effect” by enhancing firms’ information and competitive advantages. Further heterogeneity analysis reveals that the relationship between AI and the supplier “lock-in effect” is influenced by national policies and local tax burdens, and is significant only among manufacturing firms.