Abstract:Relying on the research project for 14th Five-Year Plan in business administration discipline of National Natural Science Foundations of China, this study puts forward the theoretical framework and research topics of technological innovation management through literature review and expert interview. The research topics include: corporate strategy-oriented technological innovation management, process mechanism in product innovation, evaluation and optimization in process innovation, and influencing mechanism of organizational, technological and contextual factors on technological innovation management. Finally, the study condenses the key scientific problems in the field of technological innovation management which include the research on the fundamental theory and method in innovation management by employing digital technology and big data, the research on the Chinese context specificity and innovation management theory and practice, the research on the innovation catch-up mechanism and path of Chinese enterprises, the research on the innovation mechanism and path of key core technology, the research on the structure, evolution and governance mechanism of innovation ecosystem, and micro mechanism of innovation behavior.