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Journal of Nursing ›› 2018, Vol. 25 ›› Issue (20): 24-30.doi: 10.16460/j.issn1008-9969.2018.20.024

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Effect of Enteral Nutritional Supplements on Prevention and Treatment of Pressure Ulcers: A Systematic Review

ZHAO Shi-yu, KE Hui, LI Meng-yuan, XIONG Can, YU Jiao-hua   

  1. Affiliated Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China
  • Received:2018-04-03 Published:2020-07-06

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Abstract: Objective To systematically evaluate the clinical effects of enteral nutrition supplements on the prevention and treatment of pressure ulcers. Methods Randomized controlled trials (RCTs) were retrieved from CNKI, WanFang database, VIP, Cochrane Library, Medline, EMbase, Web of Science and PubMed. RevMan 5.3 software was used for statistical analysis after the literature quality was evaluated strictly and the data was extracted. Results Twenty RCTs were included. Meta-analysis showed that enteral nutrition supplements could reduce the incidence of pressure ulcers [RR=0.81,95%CI(0.71,0.91), P=0.0008], improve the cure rate of pressure ulcer [RR=1.53,95%CI(1.28,1.83), P<0.00001] and reduce pressure ulcer area [SMD=-1.11,95%CI（-1.39,-0.82）,P<0.00001] without increasing the incidence of adverse reactions [RR=0.78,95%CI(0.37,1.63), P=0.51] but it could not reduce the healing score of pressure ulcers [MD=-0.68,95%CI(-1.47, 0.1), P=0.09]. Conclusion Enteral nutrition supplements have advantages in reducing the incidence of pressure ulcer, improving the cure rate of pressure ulcer and reducing the area of pressure ulcer,while the effect of reducing pressure ulcer healing score and shortening the healing time and whether increasing the incidence of adverse reactions is still not certain. Large and high-quality randomized controlled trials are needed to confirm its effect.

Key words: enteral nutrition, nutritional supplement, pressure sore, systematic review

CLC Number: 

  • R248.1
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