Based on market-oriented theory and R&D-marketing interface integration theory, this research takes the R&D-marketing interface integration process of Haier as a case study, to explore models of R&D-marketing interface co-evolution path, mechanism of Chinese enterprise, to explain that how Haier is based on market-oriented R&D-marketing interface integration, how Haier forms the integration flow loops of screen, test and feedback, and how Haier achieves a rapid response mechanism to market explaining its process, reasons and characteristics. The research results to improve new product performance, to eliminate the three major obstacles of R&D-marketing Interface integration: information communication barrier, resources integration obstacle, target coordination disorder, having great theoretical value and practical significance.