Considering the collaboration features of complicated technological innovation, the game theory model was built for innovation cooperation in knowledge-based enterprise's internal innovation network. The model was resolved and its solution was simulated numerically.It is concluded that node's input strategy has positive correlation with output elasticity and other node's innovation capacity increases when the node's innovation capacity is below a lever, and etc.  Based on these conclusions, the strategy advice of the innovation inspiration is given for knowledge-based enterprise's internal innovation network.