The relationship between network ties and entrepreneurial performance has been widely studied by scholars, but there are controversial conclusions in those researches. Through a dynamic tracking of case studies of six new ventures, this study has explored the mechanism of the effect of network ties on firm performance in ventures’ growth, and introduces one contingency factor: trust, to explore its effect on the relationship between network ties and firm performance. The results show: ①From entrepreneurial opportunity exploitation to new venture growth, the role of strong ties gradually decreases, and the role of weak ties gradually increases.②In the stage of entrepreneurial opportunity exploitation, affective trust has a mediating effect on the relationship between strong ties and entrepreneurial performance.③In the stage of new venture growth, cognitive trust has a positive moderating effect on the relationship between weak ties and entrepreneurial performance.