Abstract Using a sample of 466 employees from the companies in China, this study examines the relationship between human resource practices (HRP) and WDB. This study finds out that:1) HRP, such as employee participation, employment security, incentive compensation, and developmental performance appraisal can directly affect WDB; b) the employee’s job satisfaction has a partially mediating effect on the relationships of HRP and WDB. This study proves that using human resource management practices can decrease WDB to some extent.