How to alter the unfavorable position of domestic retail enterprises in the competition has become an important subject both in the academia and the business. Enlightened by the thought about virtual enterprises advanced in the manufacturing and the special development case of Meiyijia, an original retail virtual enterprise model and the solution to supply chains based on service ability is proposed. The practice possibility, improvement of management and the profit mode were analyzed according to Meiyijia case. The case study shows that the retail virtual enterprise model has transformed from selling commodities to selling services, from profiting by price difference to profiting by services-added values, making the retailer enterprises develop well at a lower cost.